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RACHMAT HIDAYAT
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hanifmedisiana@gmail.com
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Jl. Sirna Raga no 99, 8 Ilir, IT3 Palembang
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INDONESIA
Jurnal RSMH Palembang
Published by HM Publisher
ISSN : -     EISSN : 27742970     DOI : https://doi.org/10.37275/jrp
Core Subject : Health,
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health
JRP covers the major topics like Internal Medicine, Obstetric and Gynecology, Pediatric, Surgery, Ear Nose Throat, Neurology, Ophthalmology, Dermatovenerology, Anesthesia and Reanimation, Radiology, Pathology Anatomy, Clinical Pathology, Community Enpowerment, Manajemen of Hospital, Community Medicine and all topics related medical fields.
Arjuna Subject : Kedokteran - Kedokteran (Lain-Lain)
Articles 5 Documents
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Search results for , issue "Vol. 1 No. 1 (2020): Jurnal RSMH Palembang" : 5 Documents clear
Effectiveness Of Ranitidine Providing Compared With Omeprazol In Children With Gastroesofageal Reflux Disease Hasri Salwan; Rizki Nandasari Sulbahri; Raden Muhammad Indra; Sri Kesuma Astuti
Jurnal RSMH Palembang Vol. 1 No. 1 (2020): Jurnal RSMH Palembang
Publisher : RSUP Dr Moh Hoesin Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (418.133 KB) | DOI: 10.37275/jrp.v1i1.1

Abstract

Background. The drugs that are often given to children with GERD are stomach acidsuppressants, namely the H2 receptor antagonist and proton pump inhibitor (PPI) classof drugs, but the effectiveness of the two drugs is still controversial. Objective. Toevaluate the use of PPIs and H2 RA in children with GERD through evidence-basedcase studies. Methods. Systematic search for literature using the search instrumentPUBMED, Cochrane, Google Scholar, Pediatrica Indonesiana, and Sari Pediatri.Searches included systematic review articles, randomized controlled clinical trials andcohort studies. Abstract only studies, non-clinical evaluation results, and case reportswere excluded. Results. The study was obtained from three RCT studies comparingthe effectiveness of omeprazole and ranitidine in the treatment of GERD, all of whichhave differences. Azizollahi et al demonstrated that after 2 weeks of standard doses ofomeprazole or ranitidine there was a comparable significant improvement. Ummarinoet al demonstrated that omeprazole was significantly better than high-dose ranitidine.Cucchiara et al (1993) showed that high doses of ranitidine were as good as omeprazole.Another study by Pfefferkorn et al showed no significant effect on the addition ofomeprazole therapy combined with ranitidine in preventing the incidence of NAB. Astudy by Boccia et al comparing omeprazole, ranitidine, and non-therapy, found verylow relapse rates. Conclusion. Evidence regarding the use of ranitidine versusomeprazole in infants and children is lacking. Based on one study specifically in theinfant age group, omeprazole and ranitidine were of comparable effectiveness. A higherdose of ranitidine may have a better effect. In terms of complete symptom relief,omeprazole is likely to be superior to ranitidine.
Stromal Tumors in the Prostate Aspitri ani; Kurniawan Dedy
Jurnal RSMH Palembang Vol. 1 No. 1 (2020): Jurnal RSMH Palembang
Publisher : RSUP Dr Moh Hoesin Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (955.164 KB) | DOI: 10.37275/jrp.v1i1.2

Abstract

Stromal tumors of the prostate are rare mesenchymal tumors of the prostate stroma,in the form of spindle cell tumors, which are differentiated by cellularity, mitotic index,cellular atypia, and necrosis. These tumors are classified into two; prostatic stromaltumors of uncertain malignant potential (STUMP) and prostatic stromal sarcomas (PSS).The incidence is about 0.1-0.2% of the total incidence of prostate cancer. Thepathogenesis of prostate stromal tumors is based on origin, clonal and chromosomalabnormalities. Clinical symptoms of complaints lead to lower urinary tract obstruction,dysuria and pollakiuria as well as abnormalities in the rectal toucher (RT) examination.Macroscopically, brownish-white masses were found showing a solid or solid-cysticpattern. Radiological examination can use transrectal ultrasound (TRUS), CT Scan andMRI. Histopathologically, prostate STUMP has five different patterns, namely thedegenerative atypia pattern, hypercellular stroma pattern, phyllodes-type growthpattern, myxoid pattern, and epithelioid stromal pattern. Meanwhile, in PSS, there arehistological patterns of storiform, epithelioid, fibrosarcomatous, and patternless growthpatterns. Then PSS was subclassified into two, namely low grade and high gradetumors. Immunohistochemical examination showed immunoreactivity for CD34, PR,smooth muscle actin (SMA), desmin, HHF35, smooth muscle actin, vimentin andandrogen receptors and negative for estrogen receptors, CD117 and S-100. Thedifferential diagnosis is rhabdomyosarcoma, leiomyosarcoma, inflammatorymyofibroblastic tumor, sarcomatoid carcinoma, benign prostate hyperplasia, smoothmuscle tumor, gastrointestinal stromal tumor, and solitary fibrous tumor. Prognosis ofprostate STUMP is better than that of PSS. Treatment of STUMP is currently unknown.Definitive resection can be performed taking into account the patient's age, treatmentpreference, and the size or size of the lesion. Treatment for PSS radical prostatectomy,cystoprostatectomy, or pelvic exenteration for local aggressive tumors.
Black Dot Type Capitis Tinea Appreciates Bacterial Foliculitis Radema Maradong Ayu Pranata; Rusmawardiana; Fifa Argentina
Jurnal RSMH Palembang Vol. 1 No. 1 (2020): Jurnal RSMH Palembang
Publisher : RSUP Dr Moh Hoesin Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (657.944 KB) | DOI: 10.37275/jrp.v1i1.3

Abstract

Tinea capitis is a superficial fungal infection of the scalp and hair, which is seenpredominantly in children. In adults, it is usually related to immunocompromisedpatients and have an atypical features. In patients with end stage renal disease (ESRD),uremia is associated with immune suppression due to the impact of uremic milieu. Allspecimens of tinea capitis should be examined for microscopy, wood’s lamp andculture. Reported a case of 50–year-old male, animal husbandry, presented with itchypapules, pustules, patch alopecia and a hair loss for 6 months. Dermatologic featuresshowed papules, pustules, patch alopecia and black dot. The patient treated withketoconazole shampoo for 3 weeks without any improvement. He had an ESRD for 2years. Gram stain examination and culture showed no bacteri. Wood’s lampexamination showed no fluorescent. Potassium hydroxide (KOH) 10% from scalpscrapings and KOH 20% from hair showed a fungal elements, which support diagnosisof black dot tinea capitis. The patient treated with griseofulvin tablet 500 mg twice aday for 8 weeks, cetirizine tablet 10 mg once daily and 3x/week of ketoconazoleshampoo 2% showed improvement in clinical features and microscopic evaluation.
Role of Cathelicidin (Ll-37) and Human Β-Defensin In Atopic Dermatitis And Psoriasis Febrina Andarini; Nopriyati; Sarah Diba
Jurnal RSMH Palembang Vol. 1 No. 1 (2020): Jurnal RSMH Palembang
Publisher : RSUP Dr Moh Hoesin Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (731.664 KB) | DOI: 10.37275/jrp.v1i1.4

Abstract

The Human epithelium, including the epidermis produces antimicrobial peptide (AMP)as part of innate immunity. Cathelicidin and human β-defensins are the most AMPfound on the skin. This antimicrobial peptide has a role in the response of the naturalimmune system by becoming the front line of the defense system against infection. Thediscussion of this literature review will focus on cathelicidin and human β-defensin-1which are the main AMPs that affect atopic dermatitis and psoriasis. Antimicrobialpeptides are excessively produced in lesional psoriatic scales or rosacea in contrast tothe atopic skin that shows lower AMP levels when compared with psoriasis. Despitethe impaired skin barrier which facilitates potentially pathogenic microbes to colonizethe epidermis, patients with psoriasis surprisingly present a low frequency of skininfections, whereas patients with atopic dermatitis are predominantly susceptible toparticular cutaneous bacterial, fungal and viral infections. One possible explanation ofthe fact is the difference in the expression of AMPs. DA patients have fewer AMPexpression characteristics, especially cathelicidins LL-37 and HBD-2. Research onantimicrobial use can help reduce pathogen colonization so that clinical improvementof AD occurs. In the case of psoriasis, AMP expression increases, especially LL-37 andHBD-2, showing synergistic antimicrobial activity that is effective in eradicatingmicrobial colonization, so there is no strong evidence to support antibiotic use intreating psoriasis or in preventing disease.
Superficial mycosis profile in the Tertiary Hospital Dr. Moh. Hoesin Palembang: retrospective research Desi Harnis; Rusmawardiana; , Fifa Argentina
Jurnal RSMH Palembang Vol. 1 No. 1 (2020): Jurnal RSMH Palembang
Publisher : RSUP Dr Moh Hoesin Palembang

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (778.281 KB) | DOI: 10.37275/jrp.v1i1.5

Abstract

Background Superficial mycoses is a fungal infection of the skin, nails and hair thatcaused by dematophytes, yeast and mold. Superficial mycoses infections are commonlyfound in high temperature and humidity area such as Indonesia. Palembang is one ofregions in Indonesia has a high temperature and humidity, considered the incidenceof this disease is high. A retrospective study of new cases of superficial mycoses, datataken from medical records and register book at Policlinic of Dermatology andVenereology Dr. Moh. Hoesin Palembang during 5 years from January 2014-December2018. There were 1,236 (17.1%) new cases of superficial mycoses. Incidence ofsuperficial mycoses varies with range 6.9%-23%. The most common superficialmycoses is dermatophytes (38,3%). Microsporum canis, Trichophyton rubrum danTricophyton hmentagrophytes are frequent isolates in this study. The most age groupis 36-45 years (17.6%) with male more than female. Superficial mycoses are often foundin students (26.9%), followed by unskilled workers (20.8%). Of the 1,236 new cases,125 patients had comorbidities, such as malignancy 21 (16.8%) patients,cerebrovascular disease and diabetes mellitus each 16 patients (7.4%). Inguinal andabdomen are the most commonly infected regions. 656 (53.1%) patients was giventopical antifungal. The most common topical antifungal was ketoconazole 2% cream(62%) and systemic antifungal was itraconazole (55,3%).Conclusion: Cases ofsuperficial mycoses, especially dermatophytosis and Malassezia were still commonlyfound, especially in Palembang.

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